Researchers regularly request direct use of residual material from routine care, often for a single study. In these cases there is no storage of the material before its use. Also, for technical reasons previous storage is sometimes not possible, for instance when material is no longer suitable for experiments after freezing and thawing. In some cases, there is no material left for storage for future research after the direct use in a scientific study.

For direct use of (fresh) residual human biological material from routine care in a scientific study, a simplified TCBio procedure is in place provided a set of criteria can be met. The instruction can be downloaded here: